CHAPPAQUA, N.Y. - nvtip -- Metadichol®, a nano lipid formulation of long chain alcohols, has been shown in vitro studies to be an anti-viral for SARS-COV-2 (the COVID-19 virus) and it does so by blocking the cell entry points for SARS-COV-2. The receptor ACE2 is used by the virus for entry and the serine protease TMPRSS2 for S protein priming.  It inhibits both ACE2 and TMPRSS2. An anti-viral assay against the virus using CACO2 cells showed that it had an EC90 of 0.16 µg/ml, which means it effectively eliminates the virus at a very low concentration.

Metadichol® inhibits TMPRSS2 (EC50 of 96 ng/ml). It is 270 times more potent than another another well known inhibitor Camostat mesylate, which has EC50 of (26000 ng/ml). Metadichol is also a moderate inhibitor of ACE2 with an EC50 of 31 µg/ml. Moderate inhibition of ACE2 allows it to perform its key functions in the body, yet fend off SARS-COV-2 entry to the cell. ACE2 lowers blood pressure, regulates intestinal neutral amino acid transport. ACE2 expression and function is increasingly recognized as a potential therapeutic strategy in hypertension and cardiovascular disease, diabetes, lung injury, and fibrotic disorders.

More on nvtip.com

• Boulder City Hospital To Change Provider Type
• $317M Revenue and a Clear Path to $1B: $IQST is Positioned for a Major Profitability Inflection
• ASI Hosts 2026 Executive Business Summit for Global Partner Community
• Modernization Expert Jeff Miller Outlines "Version 2.0" Plan for Clark County Election 2026
• Pastor Saeed Abedini Releases THE TRUTH – Volume 1, A Deeply Personal Story of Faith, Struggle, and Redemption

Metadichol, by binding to the Vitamin D receptor (VDR), acts on proteases like Furin and Adam-17, which activate the S-protein spikes for viral spread and pathogenesis in the infected hosts. In Malaria, CD147,  also known as Basigin, is used by parasites to gain entry into the cell. Recent publications suggest that it also can be used as a point of entry by the SARS-COV-2 virus. Our previous work (US patent 9,006,292) showed that Metadichol is also potent against Malarial parasites and, by association, CD147. All these results and others are documented in our recent publication available at  (https://www.researchsquare.com/article/rs-34021/v1)

A pilot study (outside the USA) on five COVID-19 patients with minor symptoms showed the absence of a virus after 2-4 days of Metadichol @ 20 mg per day. To validate this further, we have initiated a study in collaboration with government agencies. The initial study of 30 patients showed 75% of the patients cleared of the SARS-COV-2 virus after 4 days of treatment - see http://nanorxeurope.com/Documents/India-hospital-letter.pdf.

More on nvtip.com

• New Book Warring From the Standpoint of the Throne Room Calls Believers to Pray From Victory
• Scotch Whisky Market Dislocation Creates Compelling Entry Opportunity for Long-Term Investors
• Peccioli Becomes New Orleans: In July 2026, the magic of jazz comes to Tuscany
• Jeff Miller Launches Clark County Clerk Bid: Replacing 1909 Systems with Version 2.0
• $6 Million Funding Secured as Retail Expansion, Operational Streamlining, and Asset-Light Strategy Position the Company for Accelerated Growth $SOWG

Metadichol is a safe, non-toxic product made from renewable sources and commercially available with no reported side effects. This unique property allows for the use of Metadichol in a situation that exists today and also to prevent future occurrence of SARS-COV-2 and other infections, and use of it worldwide would allow normal human activity everywhere.

Patent details and publications can be found at https://www.researchgate.net/profile/Palayakotai_Raghavan.
Metadichol, marketed as Nano Soma can be found at www.thenanosoma.com and http://www.nanosoma.net, whilst Nano-Ojas can be found at www.nanoojas.net and Metadichol at www.gen100.com.
Metadichol is available as an oral or topical spray, a topical (or oral) gel and a face cream.

For further information contact:
media_relations@nanorxeurope.com
+1 443 769 1752 (USA)
+44 1212 840 929 (UK)
+61 3 9021 6920 (AUSTRALIA)
+31 30 808 045 (HOLLAND)
+91 98194 85080 (INDIA)